(Formerly numbered M105.) Lecture, four hours; discussion, one hour; outside study, seven hours. Enforced requisites: Chemistry 20A, 20B, Physics 1C. Introduction to underlying science encompassing structure, properties, and fabrication of technologically important nanoscale systems. New phenomena that emerge in very small systems (typically with feature sizes below few hundred nanometers) explained using basic concepts from physics and chemistry. Chemical, optical, and electronic properties, electron transport, structural stability, self-assembly, templated assembly and applications of various nanostructures such as quantum dots, nanoparticles, quantum wires, quantum wells and multilayers, carbon nanotubes. Letter grading.