Lecture, three hours; discussion, one hour. Preparation: three and one half years of high school mathematics (including trigonometry). Enforced requisite: successful completion of Mathematics Diagnostic Test (score of 48 or better) or course 1 with grade of C- or better. Not open for credit to students with credit in another calculus sequence. Modeling with functions, limits, and derivatives, decisions and optimization in biology, derivative rules and tools. P/NP or letter grading.