Lecture, two hours; outside study, four hours. Designed for graduate students. Introduction to research topics and issues in medical informatics for students new to field. Definition of this emerging field of study, current research efforts, and future directions in research. Key issues in medical informatics to expose students to different application domains, such as information system architectures, data and process modeling, information extraction and representations, information retrieval and visualization, health services research, telemedicine. Emphasis on current research endeavors and applications. S/U grading.