Lecture, four hours (10 weeks); clinical, 24 hours (five weeks). Requisite: course 162B. Nursing assessment and management of acute and chronic health problems of acutely ill adults. Content in assessment, health history, and diagnostic reasoning with emphasis on social, cultural, and developmental influences. Integration of pathophysiology, pharmacology, stress and adaptation, adult development theory, therapeutic interventions, evidence-based practice, patient safety, and communication concepts as applied to care of acutely ill medical surgical patients, with complex and comorbid conditions, and their families. Emphasis on critical and contextual thinking skills and diagnostic reasoning. Nursing process, ethical principles, clinical research, evidence-based practice, and clinical thinking that maximize patient safety and quality care. Diagnosis and management of health care problems managed by master's-level clinical nurses in acute care settings. Letter grading.