Lecture, three hours; discussion, two hours. Enforced requisite: course 73A. Limited to first-year freshmen. Drawing on several disciplines including disability studies, literary and film analysis, neurobiology, philosophy, and psychology, development of multilayered account of how our increasingly sophisticated knowledge of brain relates to experiences of subjectivity, mental health, and disability. Explicitly addresses considerations regarding diversity by examining questions about variation in mental functioning and experience, with specific attention to the way ableism shapes our views about psychiatric and brain-based difference. P/NP or letter grading.