Lecture, four hours; outside study, eight hours. Requisite: course 201. Designed for graduate students with one to two years work experience. Integrated logistic support (ILS) is major driver of system life-cycle cost and one key element of system engineering activities. Overview of engineering disciplines critical to this function--reliability, maintainability, and supportability--and their relationships, taught using probability theory. Topics also include fault detections and isolations and parts obsolescence. Discussion of 6-sigma process, one effective design and manufacturing methodology, to ensure system reliability, maintainability, and supportability. Letter grading.