Lecture, four hours; discussion, one hour; outside study, seven hours. Enforced requisite: course 102A. Fundamentals of classical and statistical thermodynamics in chemical and biological sciences. Phase equilibria in single and multicomponent systems. Thermodynamics of ideal and nonideal solutions. Chemical reaction equilibria. Statistical ensembles and partition functions. Statistical thermodynamics of ideal gases. Intermolecular interactions and liquid state. Thermodynamics of polymers and biological macromolecules. Letter grading.