Lecture, three hours. Limited to Genetic Counseling students, and open to medical genetics, molecular and cytogenetics fellows with permission. Third course in three-course series. Focus on medical approaches to clinical genetics. Topics include overview of various pediatrics, adult-onset and biochemical genetic disorders, newborn screening, and current treatments of genetic disorders. Addresses application of medical and genetic information to genetic counseling. Includes lectures, problem-based learning scenarios, examinations, and reflections. Grand Rounds/Seminar series attendance is required component. Letter grading.