Lecture, three hours; laboratory, six hours. Requisites: Life Sciences 4 or 107, 23L. Course 187AL is requisite to 187BL. Limited to Molecular, Cell, and Developmental Biology majors. Introduction to cutting-edge genomic technologies and bioinformatics methods and resources for genome annotation. Students propose original research projects related to gene annotation and drive their projects using bioinformatics tools. Students are provided fragments of genome from relatively poorly studied organism that has been sequenced at UCLA. May not be repeated for credit. Letter grading.