Lecture, four hours; outside study, eight hours. Introduction to modern topics in drug delivery devices and relevant biomedical applications. Topics provide comprehensive and critical examination of current and emerging research and development on drug delivery devices, with emphasis on innovation and translation. Topics include bioresponsive drug delivery systems, drug delivery reservoirs, MEMS and micro/nanorobots for drug delivery, nanomedicine-device combination products, and development and regulation of drug delivery devices. Students acquire theoretical and practical knowledge of drug delivery devices. Students gain ability to identify advanced approaches for drug delivery mediated by devices in effective and safe manner, from systemic administration to site-specific release; design appropriate mechanisms, materials, and structures for engineering drug delivery devices to deliver different therapeutics for treating variety of diseases; and propose methods and relevant experiments to validate efficacy of certain drug delivery devices. Letter grading.