(Same as Physics and Biology in Medicine M229.) Lecture, four hours. Requisite: course M219. Designed for students interested in pursuing research related to development or translation of new magnetic resonance imaging (MRI) technique. Basic tools and understanding of recent MRI developments that have had high impact on field, involve novel pulse sequence design or image reconstructions, and enable imaging of anatomy or function in way that surpasses what is currently possible with any modality. Topics include in-depth sequence simulation, RF pulse design, rapid image acquisition, parallel imaging, compressed sensing, image reconstruction and processing, motion encoding and compensation, chemical-shift imaging and understanding, and understanding/avoiding artifacts. Programming exercises in MATLAB to provide hands-on experience. Letter grading.