Lecture/laboratory, three hours. Requisite: course 440. Designed for acute-care pediatric nurse practitioner students. Advanced diagnostic reasoning and skills in management of infants, children, and adolescents with complex acute, critical, and chronic health conditions. Focus on expanding knowledge of pediatric assessment and management of selected health conditions to aspects of diagnostic tests, test interpretation, and invasive procedures to stabilize or monitor acute, critical, or chronic pediatric patient. Lectures and other learning activities demonstrate application and evaluation of evidence-based research and clinical guidelines in pediatric population. Letter grading.