(Same as Molecular, Cell, and Developmental Biology M140.) Lecture, three hours; discussion, one hour. Requisite: Molecular, Cell, and Developmental Biology 165A. Cancer causes and genetics. Effects of cell transformation on cell growth and metabolism. Altered cell cycle, metabolism, and differentiation pathways in cancer cells. Tumor microenvironment contributions to cancer malignancy, including angiogenesis, metastasis, and immune system evasion. Letter grading.