(Same as Computer Science CM224 and Human Genetics CM224.) Lecture, four hours; discussion, two hours; outside study, six hours. Requisites: Computer Science 32 or Program in Computing 10C with grade of C- or better, Mathematics 33A, and one course from Civil Engineering 110, Electrical and Computer Engineering 131A, Mathematics 170A, Mathematics 170E, or Statistics 100A. Designed for engineering students as well as students from biological sciences and medical school. Introduction to computational analysis of genetic variation and computational interdisciplinary research in genetics. Topics include introduction to genetics, identification of genes involved in disease, inferring human population history, technologies for obtaining genetic information, and genetic sequencing. Focus on formulating interdisciplinary problems as computational problems and then solving those problems using computational techniques from statistics and computer science. Letter grading.