Lecture, two hours; laboratory, six hours; outside study, four hours. Enforced requisite: course 177A. Lectures, seminars, and discussions on aspects of biomedical device and therapeutic design, including meetings with scientific/clinical advisers and guest lectures from scientists in industry. Working in teams, students develop innovative solutions to address current problems in medicine and biology. Students conduct directed experiments and computational modeling, give oral presentations, write reports, and participate in bioengineering design competition. Letter grading.