Lecture, three hours. Requisites: courses 238A, 238B, 237A, 437A. Corequisite: course 437B. Second course in two-course sequence for acute care pediatric nurse practitioner student. Focus on pathophysiology of specific disease processes, pharmacologic knowledge, clinical decision-making, and treatment modalities in managing complex acute, critical, and chronic health conditions in infants, children, and adolescents. Cultural sensitivity, child development, family support, ethical issues, and palliative care/end of life care integrated into select acute/chronic conditions. Lectures and other learning activities demonstrate application and evaluation of evidence-based research and clinical guidelines in pediatric population. Letter grading.