Lecture, three hours; laboratory, three hours. Requisite: Life Sciences 1 or 7B. Recommended: one introductory statistics course. Modern comparative biology provides framework for studying broad questions in evolution--How do body shapes evolve? What are dynamics of evolutionary arms race? Why are there so many species in tropics? Why are there so many beetles and so few crocodiles? Did dinosaurs put brakes on diversification of mammals? Examination of why tree of life is essential to understanding patterns of biological diversity and how phylogenetic comparative methods are used to test macroevolutionary hypotheses. Concurrently scheduled with course C230. Letter grading.